{"id":2569,"date":"2024-01-29T10:58:04","date_gmt":"2024-01-29T10:58:04","guid":{"rendered":"http:\/\/cari-mumbai.res.in\/cari\/?page_id=2569"},"modified":"2024-07-19T05:42:29","modified_gmt":"2024-07-19T05:42:29","slug":"research","status":"publish","type":"page","link":"http:\/\/cari-mumbai.res.in\/cari\/research\/","title":{"rendered":"Clinical Research"},"content":{"rendered":"\t\t
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Clinical Research Projects<\/strong><\/h2>

a. COVID-19 related<\/strong><\/h3>

Completed projects –<\/u><\/em><\/strong><\/p>

  1. Collaborative Research Project – A Randomized, Open-Label, Parallel Efficacy, Active Control, Multi-Centre Exploratory Drug Trial to Evaluate Efficacy and Safety of an Ayurvedic Formulation (AYUSH-64) as Adjunct Treatment to Standard of Care for the management of Mild to Moderate COVID-19 Patients. (AYUSH-CSIR study)<\/li>
  2. Collaborative Research Project – A Study of Ashwagandha in the Prophylaxis Against COVID-19 And Its Benefits on General Health in High-Risk Health Care Workers: A Randomized Controlled Comparison with Hydroxychloroquine Sulphate (HCQS) (Study Code: AYUSH CRD-HCW-01)<\/li>
  3. Collaborative Research Project – Assessment of Integration of Ayush into The Public Health System for Combating COVID-19 (WHO-AYUSH-PHFI study)<\/li>
  4. IMR project – A prospective non-randomized open-label controlled interventional study on the effect of Guduchi Ghan Vati\/ Sudarshan Ghan Vati as a prophylactic measure among the Containment Zone population exposed to COVID-19.<\/li>
  5. IMR project – A prospective open-label controlled interventional study on the effect of Ayurvedic Intervention (Ayurveda Raksha Kit) as a prophylactic measure in the Pandemic of COVID-19 – A community-based study.<\/li>
  6. IMR project – Documentation of efficacy of selected Ayush drugs (AYUSH-64 and Kabasura Kudineer) in COVID-19 patients in home isolation \u2013 A prospective community\u2013based study.<\/li>
  7. IMR project – A prophylactic community-based study to assess the impact of Ayu Raksha Kit in COVID-19 (SCSP).<\/li><\/ol>

    Ongoing projects \u2013 <\/u><\/em><\/strong><\/p>

    1. Collaborative Research Project – A study of Ashwagandha administration in participants vaccinated against COVID-19 on safety, immunogenicity, and protection: A randomized, double-blind, placebo-controlled, multicentric clinical trial (AYUSH-AG-VAC study)<\/li><\/ol>

      b. Cancer-Related Research<\/strong><\/p>

      Ongoing projects\u2013 <\/u><\/em><\/strong><\/p>

      1. Collaborative Research Project – Assessment of Prakriti (Ayurvedic body constitution) of patients with Cervical and Ovarian cancers.<\/li>
      2. Collaborative Research Project – A phase II trial to study the efficacy, toxicity and immunomodulatory effect of Carctol-S in high-grade serous epithelial ovarian cancer at first serological relapse in collaboration with Tata Memorial Centre (TMC) and ACTREC<\/li>
      3. Collaborative Research Project – Understanding the mechanistic role of CARAF and CAGHE as immunomodulatory and anti-cancer compounds against preclinical models of leukemia, lymphoma, myeloma, lung, and breast cancer.<\/li>
      4. Collaborative Research Project – Understanding the mechanistic role of Carctol-S as an immunomodulatory and anti-cancer formulation against ovarian cancer.<\/li>
      5. Collaborative Research Project – Ayurveda Interventions for Cancer: Systematic Review, Meta-analysis; and Revival, Documentation, Validation, and analysis of data from practitioners, institutes<\/li>
      6. Collaborative Research project – Preclinical study on efficacy, safety, and toxicity of Swarna Prashan Regimen as Adjunct therapy in pediatric acute lymphoblastic leukemia.<\/span><\/li>
      7. Collaborative Project- Assessment of Anti-aging, Antimutagenic and Cancer Chemoprevention potential of Swarna Bhasma in Drosophila melanogaster<\/span><\/li>
      8. Collaborative Project- U.S. Survey of Ayurvedic Practitioners Regarding Cancer Patient Management.<\/span><\/li><\/ol>

        \u00a0<\/p>

        c.\u00a0 <\/span>Other Clinical Research<\/b><\/p>

        Ongoing projects \u2013<\/i><\/b><\/p>

        1. Collaborative Project \u2013 A Double-Blind Double Dummy prospective randomized controlled study to evaluate the efficacy of classical Ayurveda management versus Methotrexate in RA (AMRA).<\/span><\/li>
        2. Collaborative project- Efficacy of Ayurveda interventions (Hridyarnava Rasa and Harityakyadi yoga) as an add-on to standard care in Stable Coronary Artery Disease (CAD) assessed through Global Longitudinal Strain Imaging Technique (GLSIT) – A Randomized Controlled Trial<\/span><\/li>
        3. IMR- Efficacy, Safety, and Acceptability of Ayush BR Leham as an Adjuvant to the Supplementary Nutrition Programme under ICDS in the Management of Moderate Malnutrition among Children aged 3 – 5 years from Anganwadi centers – A cluster randomized controlled clinical trial<\/span><\/li>
        4. Collaborative project- General health screening with a special focus on Tuberculosis, Anemia, Haemoglobinopathies & Malnutrition, and Ayurvedic Interventions for better health outcomes in students of Ekalavya Residential Model Schools (EMRS) functioning under M\/o Tribal Affairs<\/span><\/li>
        5. Collaborative project – Impact of Mukta Shukti Bhasma and Saubhagya Shunti Churna in a reversal of bone mineral density among lactating women consuming traditional diet foods in Maharashtra: A randomized controlled preliminary clinical study<\/span><\/li>
        6. Collaborative project \u2013 Osteoporosis Screening and Intervention Programme Using AYUSH Approach: A community-based Programme in Maharashtra state.<\/span><\/li>
        7. Collaborative Project \u2013 Systems Biology approach to delineate molecular signatures of Prakriti in healthy humans.<\/span><\/li>
        8. Central Sector Scheme of Pharmacovigilance of ASU&H Drugs.<\/span><\/li><\/ol>

          Completed projects \u2013<\/i><\/b><\/p>

          1. Collaborative Research Project \u2013 A Randomized Placebo Control Prospective Phase \u2013 2 Clinical study of an Ayurvedic Coded Drug AYUSH D in the management of Type-2 Diabetes mellitus as add on therapy to Metformin.<\/span><\/li>
          2. Collaborative Research Project – A Randomized Placebo Control Prospective Phase \u2013 2 Clinical study of an Ayurvedic Coded Drug AYUSH D on control in Pre-Diabetic subjects.<\/span><\/li>
          3. IMR project – Clinical Evaluation of Chitraka Haritaki and Lavangadi Vati in Kaphaja Kasa (Stable Chronic Bronchitis)<\/span><\/li>
          4. IMR project – An open-labeled observational study to document the potential safety issues and prescription trends in Rasaushadhi\u2019s in CCRAS-OPD\u2019s across India.<\/span><\/li>
          5. IMR project – A pilot evaluation of safety and efficacy of an Ayurvedic formulation (AYUSH 64) for accelerating the recovery in case of influenza-like illness.<\/span><\/li>
          6. IMR project – Clinical evaluation of an Ayurvedic formulation in the management of Allergic Rhinitis- A pilot study.<\/span><\/li>
          7. IMR project – Retrospective Pharmaco-Epidemiology Data Collection and Analysis of OPD\/IPD with reference to the prescription of Rasaushadhies during the last 5 years.<\/span><\/li>
          8. IMR project – Development and validation of Prakriti Assessment Scale\/Questionnaire- AYUR Prakriti of CCRAS<\/span><\/li>
          9. Reliability and validation of Ayurvedic Diagnostic Tools: Prameha Roga<\/span><\/li>
          10. Reliability and validation of Ayurvedic Diagnostic Tools: PranavahaSrotas<\/span><\/li>
          11. Reliability and validation of Ayurvedic Diagnostic Tools: Grahani Roga<\/span><\/li>
          12. Reliability and validation of Ayurvedic Diagnostic Tools: Pandu and Kamla<\/span><\/li>
          13. IMR project – Effective Implementation of A-HMIS (2020-2021).<\/span><\/li>
          14. IMR project – Efficacy and safety of Ayurveda interventions for allergic rhinitis: A systematic review.<\/span><\/li>
          15. IMR project – Systematic review and Meta-analysis of Ayurvedic interventions for Psoriasis.<\/span><\/li>
          16. IMR project – Systematic review and Meta-analysis of Ayurvedic interventions for Essential Hypertension.<\/span><\/li>
          17. IMR project – Effectiveness and safety of Ayurveda intervention in children and adolescent with ADHD: A Systematic Review with Meta-analysis.<\/span><\/li>
          18. IMR project – Efficacy and safety of Ayurveda interventions for Sinusitis- A Systematic Review.<\/span><\/li>
          19. IMR project – Efficacy and safety of Ayurveda interventions for Diabetes mellitus- A Systematic Review.<\/span><\/li>
          20. IMR project – A cross-sectional study of Cancer KAP among Ayurveda and Allopathic fraternities.<\/span><\/li>
          21. IMR project – Profiling of Demography, health status and Non communicable Diseases among Scheduled Caste population in selected states across India- A descriptive, Cross-sectional Epidemiological study.<\/span><\/li>
          22. IMR project – Clinical Evaluation of Ashwagandha on Quality of life in Geriatric population prospective Double-Blind placebo- controlled study.<\/span><\/li>
          23. IMR project – A prophylactic community-based study to assess the impact of Ayu Raksha Kit in COVID.<\/span><\/li>
          24. IMR project – A prospective community-based study for evaluation of Punarnavadi Mandura in Anemia (Pandu).<\/span><\/li>
          25. IMR project – Effectiveness of Ayurveda-based diet and Lifestyle advocacy on health-related Quality of life in schedule Caste population in India- a Community based, cluster-randomized controlled study.<\/span><\/li>
          26. IMR project – Clinical trial to study the effect of Chyavanaprasha on aging in apparently healthy elderly subjects under Annual Action plan 2013-14 .\u00a0<\/span><\/li>
          27. IMR project – Clinical evaluation of Ashwagandha Churna & Pravala Pishti in the management of Osteoporosis\/ Osteopenia under Annual Action plan 2012-13.<\/span><\/li>
          28. IMR project – Clinical evaluation of Pranada Gutika and Abhyarishta in the management of Arsha (Hemorrhoids)<\/span><\/li><\/ol>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

            Clinical Research Projects a. COVID-19 related Completed projects – Collaborative Research Project – A Randomized, Open-Label, Parallel Efficacy, Active Control, Multi-Centre Exploratory Drug Trial to Evaluate Efficacy and Safety of an Ayurvedic Formulation (AYUSH-64) as Adjunct Treatment to Standard of<\/p>\n","protected":false},"author":1,"featured_media":2602,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_eb_attr":"","footnotes":""},"class_list":["post-2569","page","type-page","status-publish","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"http:\/\/cari-mumbai.res.in\/cari\/wp-json\/wp\/v2\/pages\/2569","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/cari-mumbai.res.in\/cari\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/cari-mumbai.res.in\/cari\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/cari-mumbai.res.in\/cari\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/cari-mumbai.res.in\/cari\/wp-json\/wp\/v2\/comments?post=2569"}],"version-history":[{"count":17,"href":"http:\/\/cari-mumbai.res.in\/cari\/wp-json\/wp\/v2\/pages\/2569\/revisions"}],"predecessor-version":[{"id":3119,"href":"http:\/\/cari-mumbai.res.in\/cari\/wp-json\/wp\/v2\/pages\/2569\/revisions\/3119"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/cari-mumbai.res.in\/cari\/wp-json\/wp\/v2\/media\/2602"}],"wp:attachment":[{"href":"http:\/\/cari-mumbai.res.in\/cari\/wp-json\/wp\/v2\/media?parent=2569"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}