Clinical Research Projects

a. COVID-19 related

Completed projects –

  1. Collaborative Research Project – A Randomized, Open-Label, Parallel Efficacy, Active Control, Multi-Centre Exploratory Drug Trial to Evaluate Efficacy and Safety of an Ayurvedic Formulation (AYUSH-64) as Adjunct Treatment to Standard of Care for the management of Mild to Moderate COVID-19 Patients. (AYUSH-CSIR study)
  2. Collaborative Research Project – A Study of Ashwagandha in the Prophylaxis Against COVID-19 And Its Benefits on General Health in High-Risk Health Care Workers: A Randomized Controlled Comparison with Hydroxychloroquine Sulphate (HCQS) (Study Code: AYUSH CRD-HCW-01)
  3. Collaborative Research Project – Assessment of Integration of Ayush into The Public Health System for Combating COVID-19 (WHO-AYUSH-PHFI study)
  4. IMR project – A prospective non-randomized open-label controlled interventional study on the effect of Guduchi Ghan Vati/ Sudarshan Ghan Vati as a prophylactic measure among the Containment Zone population exposed to COVID-19.
  5. IMR project – A prospective open-label controlled interventional study on the effect of Ayurvedic Intervention (Ayurveda Raksha Kit) as a prophylactic measure in the Pandemic of COVID-19 – A community-based study.
  6. IMR project – Documentation of efficacy of selected Ayush drugs (AYUSH-64 and Kabasura Kudineer) in COVID-19 patients in home isolation – A prospective community–based study.
  7. IMR project – A prophylactic community-based study to assess the impact of Ayu Raksha Kit in COVID-19 (SCSP).

Ongoing projects –

  1. Collaborative Research Project – A study of Ashwagandha administration in participants vaccinated against COVID-19 on safety, immunogenicity, and protection: A randomized, double-blind, placebo-controlled, multicentric clinical trial (AYUSH-AG-VAC study)

b. Cancer-Related Research

Ongoing projects–

  1. Collaborative Research Project – Assessment of Prakriti (Ayurvedic body constitution) of patients with Cervical and Ovarian cancers.
  2. Collaborative Research Project – A phase II trial to study the efficacy, toxicity and immunomodulatory effect of Carctol-S in high-grade serous epithelial ovarian cancer at first serological relapse in collaboration with Tata Memorial Centre (TMC) and ACTREC
  3. Collaborative Research Project – Understanding the mechanistic role of CARAF and CAGHE as immunomodulatory and anti-cancer compounds against preclinical models of leukemia, lymphoma, myeloma, lung, and breast cancer.
  4. Collaborative Research Project – Understanding the mechanistic role of Carctol-S as an immunomodulatory and anti-cancer formulation against ovarian cancer.
  5. Collaborative Research Project – Ayurveda Interventions for Cancer: Systematic Review, Meta-analysis; and Revival, Documentation, Validation, and analysis of data from practitioners, institutes
  6. Collaborative Research project – Preclinical study on efficacy, safety, and toxicity of Swarna Prashan Regimen as Adjunct therapy in pediatric acute lymphoblastic leukemia.
  7. Collaborative Project- Assessment of Anti-aging, Antimutagenic and Cancer Chemoprevention potential of Swarna Bhasma in Drosophila melanogaster
  8. Collaborative Project- U.S. Survey of Ayurvedic Practitioners Regarding Cancer Patient Management.

 

c.  Other Clinical Research

Ongoing projects –

  1. Collaborative Project – A Double-Blind Double Dummy prospective randomized controlled study to evaluate the efficacy of classical Ayurveda management versus Methotrexate in RA (AMRA).
  2. Collaborative project- Efficacy of Ayurveda interventions (Hridyarnava Rasa and Harityakyadi yoga) as an add-on to standard care in Stable Coronary Artery Disease (CAD) assessed through Global Longitudinal Strain Imaging Technique (GLSIT) – A Randomized Controlled Trial
  3. IMR- Efficacy, Safety, and Acceptability of Ayush BR Leham as an Adjuvant to the Supplementary Nutrition Programme under ICDS in the Management of Moderate Malnutrition among Children aged 3 – 5 years from Anganwadi centers – A cluster randomized controlled clinical trial
  4. Collaborative project- General health screening with a special focus on Tuberculosis, Anemia, Haemoglobinopathies & Malnutrition, and Ayurvedic Interventions for better health outcomes in students of Ekalavya Residential Model Schools (EMRS) functioning under M/o Tribal Affairs
  5. Collaborative project – Impact of Mukta Shukti Bhasma and Saubhagya Shunti Churna in a reversal of bone mineral density among lactating women consuming traditional diet foods in Maharashtra: A randomized controlled preliminary clinical study
  6. Collaborative project – Osteoporosis Screening and Intervention Programme Using AYUSH Approach: A community-based Programme in Maharashtra state.
  7. Collaborative Project – Systems Biology approach to delineate molecular signatures of Prakriti in healthy humans.
  8. Central Sector Scheme of Pharmacovigilance of ASU&H Drugs.

Completed projects –

  1. Collaborative Research Project – A Randomized Placebo Control Prospective Phase – 2 Clinical study of an Ayurvedic Coded Drug AYUSH D in the management of Type-2 Diabetes mellitus as add on therapy to Metformin.
  2. Collaborative Research Project – A Randomized Placebo Control Prospective Phase – 2 Clinical study of an Ayurvedic Coded Drug AYUSH D on control in Pre-Diabetic subjects.
  3. IMR project – Clinical Evaluation of Chitraka Haritaki and Lavangadi Vati in Kaphaja Kasa (Stable Chronic Bronchitis)
  4. IMR project – An open-labeled observational study to document the potential safety issues and prescription trends in Rasaushadhi’s in CCRAS-OPD’s across India.
  5. IMR project – A pilot evaluation of safety and efficacy of an Ayurvedic formulation (AYUSH 64) for accelerating the recovery in case of influenza-like illness.
  6. IMR project – Clinical evaluation of an Ayurvedic formulation in the management of Allergic Rhinitis- A pilot study.
  7. IMR project – Retrospective Pharmaco-Epidemiology Data Collection and Analysis of OPD/IPD with reference to the prescription of Rasaushadhies during the last 5 years.
  8. IMR project – Development and validation of Prakriti Assessment Scale/Questionnaire- AYUR Prakriti of CCRAS
  9. Reliability and validation of Ayurvedic Diagnostic Tools: Prameha Roga
  10. Reliability and validation of Ayurvedic Diagnostic Tools: PranavahaSrotas
  11. Reliability and validation of Ayurvedic Diagnostic Tools: Grahani Roga
  12. Reliability and validation of Ayurvedic Diagnostic Tools: Pandu and Kamla
  13. IMR project – Effective Implementation of A-HMIS (2020-2021).
  14. IMR project – Efficacy and safety of Ayurveda interventions for allergic rhinitis: A systematic review.
  15. IMR project – Systematic review and Meta-analysis of Ayurvedic interventions for Psoriasis.
  16. IMR project – Systematic review and Meta-analysis of Ayurvedic interventions for Essential Hypertension.
  17. IMR project – Effectiveness and safety of Ayurveda intervention in children and adolescent with ADHD: A Systematic Review with Meta-analysis.
  18. IMR project – Efficacy and safety of Ayurveda interventions for Sinusitis- A Systematic Review.
  19. IMR project – Efficacy and safety of Ayurveda interventions for Diabetes mellitus- A Systematic Review.
  20. IMR project – A cross-sectional study of Cancer KAP among Ayurveda and Allopathic fraternities.
  21. IMR project – Profiling of Demography, health status and Non communicable Diseases among Scheduled Caste population in selected states across India- A descriptive, Cross-sectional Epidemiological study.
  22. IMR project – Clinical Evaluation of Ashwagandha on Quality of life in Geriatric population prospective Double-Blind placebo- controlled study.
  23. IMR project – A prophylactic community-based study to assess the impact of Ayu Raksha Kit in COVID.
  24. IMR project – A prospective community-based study for evaluation of Punarnavadi Mandura in Anemia (Pandu).
  25. IMR project – Effectiveness of Ayurveda-based diet and Lifestyle advocacy on health-related Quality of life in schedule Caste population in India- a Community based, cluster-randomized controlled study.
  26. IMR project – Clinical trial to study the effect of Chyavanaprasha on aging in apparently healthy elderly subjects under Annual Action plan 2013-14 . 
  27. IMR project – Clinical evaluation of Ashwagandha Churna & Pravala Pishti in the management of Osteoporosis/ Osteopenia under Annual Action plan 2012-13.
  28. IMR project – Clinical evaluation of Pranada Gutika and Abhyarishta in the management of Arsha (Hemorrhoids)